At puberty one in 90 children born there make a natural transformation from girl to boy. Referred to as the ‘guevedoces’ which literally translates as ‘penis at 12’ - these children are known in medical terms as 'pseudohermaphrodite' - and feature in a new BBC 2 series called Countdown to Life - the Extraordinary Making of You.
All I wanted to do was play with the boys.” The guevedoces were uncovered by Cornell University endocrinologist Dr Julianne Imperato in the 1970s who traveled to the region to learn more about rumours that girls were morphing into boys. And in the four decades since there have been studies, more has been learned about the perfectly natural condition.
But compared to Johnny, I had it easy. “Guevedoces are also sometimes called “machihembras” meaning “first a woman, then a man.” "When they’re born they look like girls with no testes and what appears to be a vagina. "It is only when they near puberty that the penis grows and testicles descend.
“When Dr Imperato investigated the Guavadoces she discovered the reason they don’t have male genitalia at birth is because they are deficient in an enzyme called 5-α-reductase, which normally converts testosterone into dihydro-testosterone. “By a quirk of chance Dr Imperato’s research was picked up by the American pharmaceutical giant, Merck. "They used her discovery to create a drug called finasteride, which blocks the action of 5-α-reductase.
“It is now widely used to treat benign enlargement of the prostate and male pattern baldness. For which, I’m sure, many men are truly grateful.”
Sources: UK Mirror
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